Epidemiological evidence and future perspective in kidney diseases

Charat Thongprayoon, Wisit Cheungpasitporn

Mayo Clinic


Epidemiological studies have been advanced in medicine including kidney diseases. We updated epidemiological evidence in kidney diseases. For acute kidney injury, although Kidney Disease: Improving Global Outcome criteria was developed, further studies on the effects of fluid balance adjusted creatinine, minimum versus most recent baseline serum creatinine and the best surrogate baseline serum creatinine are required. For chronic kidney disease, we recently found a significant increased risk of chronic kidney disease in patients consuming sugar-sweetened soda, but not in patients consuming artificially sweetened soda. Interestingly, we found an inverse association between high alcohol consumption and risk for developing CKD in males. There is no significant association between high alcohol consumption and the risk for developing proteinuria or end-stage renal disease (ESRD). Future studies to identify these underlying mechanisms should be conducted. Journal of Nature and Science, 1(1):e28, 2015.

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